Tricor (Fenofibrate) is a lipid-lowering agent. It lowers elevated blood triglyceride levels by making the liver produce fewer triglycerides and increasing the elimination of triglycerides from the blood stream. |
Uses
Fenofibrate (FEN-oh-FYE-brate) is used for controlling high cholesterol and triglyceride levels in the blood. It is used in combination with a diet low in cholesterol and saturated fat.
How to take
Take Fenofibrate by mouth with or without food.
Swallow Fenofibrate whole. Do not break, crush, or chew before swallowing. Do not take chipped or broken tablets.
Side effects
Check with your doctor if any of these most common side effects persist or become bothersome: Headache, nausea.
Seek medical attention right away if any of these severe side effects occur: Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chills or sore throat; dark urine, fever, muscle pain, tenderness, or weakness; pale stools, red, swollen, blistered or peeling skin; severe or persistent nausea, vomiting, or stomach pain; unusual bruising or bleeding; yellowing of the skin or eyes.
This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider.
Precaution
Do NOT use Fenofibrate if: you are allergic to any ingredient in Fenofibrate;
you have gallbladder problems, liver problems (including cirrhosis), or severe kidney problems; you are breast-feeding or pregnant.
Contact your doctor or health care provider right away if any of these apply to you.
Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
if you have diabetes, underactive thyroid, heart blood vessel problems, gallstones, kidney problems, or certain muscle problems (myopathy);
if you are very overweight, have an inactive lifestyle, or you drink large amounts of alcohol.
Fenofibrate may cause dizziness or lightheadedness. These effects may be worse if you take it with alcohol or certain medicines. Use Fenofibrate with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
Lab tests, including liver function, kidney function, blood cholesterol, and other blood tests, may be performed while you use Fenofibrate. These tests may be used to monitor your condition or check for side effects. If you plan on becoming pregnant, contact your doctor. You will need to discuss the benefits and risks of using Fenofibrate while you are pregnant. It is not known if Fenofibrate is found in breast milk. Do not breast-feed while taking Fenofibrate.
Drug interactions
If you also take a bile acid binding resin (eg, cholestyramine) do not take it within 4 to 6 hours before or 1 hour after taking Fenofibrate.
Tell your health care provider if you are taking any other medicines, especially any of the following:
HMG-CoA reductase inhibitors (eg, simvastatin) because the risk of serious muscle problems leading to kidney failure may be increased;
Immunosuppressants (eg, cyclosporine) or other medicines that may harm the kidney (eg, aminoglycoside antibiotics [eg, gentamicin], amphotericin B, nonsteroidal anti-inflammatory drugs [NSAIDs] [eg, ibuprofen] tacrolimus, vancomycin) because they may decrease Fenofibrate 's excretion and increase the risk of its side effects;
Anticoagulants (eg, warfarin) or sulfonylureas (eg, glipizide) because the risk of their side effects may be increased by Fenofibrate;
Beta-blockers (eg, propranolol); estrogen, or thiazide diuretic (eg, hydrochlorothiazide).
This may not be a complete list of all interactions that may occur. Ask your health care provider if Fenofibrate may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
Missed dose
If you miss a dose of Fenofibrate, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take two doses at once.
Storage
Store Fenofibrate between 68 and 77 degrees F (20 and 25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Protect from moisture. Do not store in the bathroom. Keep Fenofibrate out of the reach of children and away from pets.
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