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Plendil (felodipine) is used to treat high blood pressure. It may be used alone or in combination with other agents. Felodipine also is used to treat patients with angina and is being studied in patients with congestive heart failure.

Uses Felodipine is used to treat high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Felodipine is known as a calcium channel blocker. By blocking calcium, this medication relaxes and widens blood vessels so blood can flow more easily This medication may also be used to prevent chest pain (angina). How to take Felodipine can be taken with a light meal or without food. The tablets should be swallowed whole, not crushed or chewed. Side effects Dizziness, lightheadedness, headache, flushing, or stomach upset may occur as your body adjusts to the medication. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Tell your doctor immediately if any of these serious side effects occur: swelling of the hands/ankles/feet (edema). Tell your doctor immediately if any of these unlikely but serious side effects occur: new or worsening chest pain, fast/irregular heartbeat. Although unlikely, felodipine may cause mild swelling of the gums. Massage your gums and brush and floss your teeth regularly to minimize this problem. See your dentist regularly. Tell your doctor immediately if any of these highly unlikely but very serious side effects occur: fainting. If you notice other effects not listed above, contact your doctor or pharmacist. Precaution Before taking felodipine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. Before using this medication, tell your doctor or pharmacist your medical history, especially of heart disease (e.g., congestive heart failure), liver disease, swelling of the arms and legs (edema). Before having surgery, tell your doctor or dentist that you are taking this medication. This drug may make you dizzy; use caution engaging in activities requiring alertness such as driving or using machinery. Limit alcoholic beverages. To minimize dizziness and lightheadedness, get up slowly when rising from a seated or lying position. Caution is advised when using this drug in the elderly because they may be more sensitive to its side effects, especially dizziness. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not known whether this drug passes into breast milk. Consult your doctor before breast-feeding Drug interactions If felodipine is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Felodipine with the following: Beta-blocking blood pressure medicines such as Lopressor, Inderal, and Tenormin Cimetidine (Tagamet) Digoxin (Lanoxin) Epilepsy medications such as Tegretol and Dilantin Erythromycin (PCE, ERYC, others) Itraconazole (Sporanox) Ketoconazole (Nizoral) Phenobarbital Theophylline (Theo-Dur) Taking felodipine with grapefruit juice can more than double the blood level of the drug. Missed dose If you miss a dose, take as soon as remembered; do not take if it is almost time for the next dose, instead, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up. Storage Store at room temperature between 59 and 86 degrees F (between 15 and 30 degrees C) away from moisture and sunlight. Do not store in the bathroom. Keep away from children and pets.

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